The opening half was punctuated by petty fouls and a red card for Hamilton's Omar Djelloul Rezgane although the decision appeared rather harsh.
There was a distinct absence of goal-scoring opportunities and goal mouth incidents although the Hamilton keeper, Raymond Jellema had to look lively to punch clear a dangerous corner in a crowded six yard area.
Clyde gave away a free kick for a foul against Richard Offiong but David Winters free kick was an easy catch for Clyde's David Hutton.
Offiong's feat almost paid dividends but Hutton was quickly off his line to foil the Accies frontman as he burst free from the defence. Offiong was frustrated at the lack of decent service and tried a spectacular effort from well outside the box which was high and wide of the target.
Fortunately the second half was better and Hamilton took the lead in the 71st minute when substitute Brian Wake set up James McArthur to score with a curling volley from the just inside the area.
Hamilton's joy was short lived however, as Clyde's man-of-the-match Neil McGregor headed the equaliser. He had stayed up in the penalty box following a free kick situation and was handily placed to divert a Chris Higgins shot passed Jellema.
The Clyde cheers had scarcely died down when the fans were in full cry once again. Hamilton's substitute Scott Tunbridge fouled Craig Bryson a yard outside the box and Eddie Malone sent his curling free kick into the top corner for a goal that was fit enough to win any match.